Apathy and depression following stroke

CNS Spectr. 2000 Mar;5(3):43-50. doi: 10.1017/s1092852900012955.


Depression and apathy are the two most frequent behavioral complications of stroke. This article reviews the prevalence of these conditions in poststroke patients, as well as their clinical correlates, longitudinal course, and possible mediators. A number of controlled clinical trials of the efficacy of various drugs in the treatment of poststroke depression are also reviewed.