Predicting an improvement of secondary catalytic activity of promiscuous isochorismate pyruvate lyase by computational design

J Am Chem Soc. 2008 Mar 12;130(10):2894-5. doi: 10.1021/ja078334c. Epub 2008 Feb 19.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon-Oxygen Lyases / chemistry
  • Catalysis
  • Chorismate Mutase / chemistry
  • Computer Simulation*
  • Enzyme Activation
  • Models, Chemical
  • Molecular Structure
  • Pseudomonas aeruginosa / enzymology*
  • Quantum Theory*

Substances

  • Carbon-Oxygen Lyases
  • Chorismate Mutase