Simultaneous protein tagging in two colors

Chem Biol. 2008 Feb;15(2):91-2. doi: 10.1016/j.chembiol.2008.02.004.


The fluorescent tagging of proteins in the natural environment of the cell is an emerging technique in cell biology. In this issue of Chemistry & Biology, Gautier et al. introduce a fluorescent labeling procedure orthogonal to existing ones, enabling tagging of two different proteins in living cells.

Publication types

  • Comment

MeSH terms

  • Alkyl and Aryl Transferases / chemistry
  • Alkyl and Aryl Transferases / metabolism
  • Color*
  • Fluorescent Dyes / analysis
  • Models, Molecular
  • Protein Structure, Tertiary
  • Proteins / chemistry
  • Proteins / metabolism*
  • Staining and Labeling / methods*


  • Fluorescent Dyes
  • Proteins
  • Alkyl and Aryl Transferases