Ten years after photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) for moderate to high myopia (control-matched study)

Br J Ophthalmol. 2009 Oct;93(10):1313-8. doi: 10.1136/bjo.2007.131748. Epub 2008 Feb 21.

Abstract

Objective: To compare the long-term outcomes of photorefractive keratectomy (PRK) and laser in situ keratomilesis (LASIK) for myopia between -6 and -10 D.

Methods: A retrospective, control-matched study including 68 eyes, 34 which underwent PRK and 34 LASIK, with myopia between -6 and -10 D, operated using the VISX 20/20 excimer laser, was performed. Optical zones of 5.5 to 6 mm were used. All PRK-treated eyes were matched with LASIK-treated eyes of the same age, spherical equivalent within +/-1.25 D, sphere within +/-1.5 D and cylinder within +/-2.5 D. All patients were evaluated 3 months, 1 year, 2 years, 5 years and 10 years after surgery. The main outcomes measures were refractive predictability and stability, safety, efficacy and re-treatment rate.

Results: At 10 years, 20 (71%) and 23 (88%) were within +/-1.00 D after PRK and LASIK respectively. The re-treatment rate was 35% and 18% respectively. No eye lost more than two lines of BSCVA in both groups. The efficacy was 0.90 for PRK and 0.95 for LASIK.

Conclusions: Both PRK and LASIK were safe for moderate myopia. LASIK demonstrated slightly better efficacy, predictability, and less rate of re-treatment after 10 years. The technical improvements should be taken into account when comparing these results with those obtained more recently.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • Follow-Up Studies
  • Humans
  • Keratomileusis, Laser In Situ / adverse effects
  • Keratomileusis, Laser In Situ / methods*
  • Male
  • Middle Aged
  • Myopia / physiopathology
  • Myopia / surgery*
  • Photorefractive Keratectomy / adverse effects
  • Photorefractive Keratectomy / methods*
  • Refraction, Ocular
  • Reoperation
  • Retrospective Studies
  • Treatment Outcome
  • Visual Acuity
  • Young Adult