Phytochemical and biological investigation of Hymenocallis littoralis SALISB

Chem Biodivers. 2008 Feb;5(2):332-40. doi: 10.1002/cbdv.200890031.

Abstract

A phytochemical investigation of the bulbs and flowers of Hymenocallis littoralis SALISB., cultivated in Egypt, was carried out, which resulted in the isolation of four alkaloids, lycorine (1), hippeastrine (2), 11-hydroxyvittatine (3), and (+)-8-O-demethylmaritidine (4), and of two flavonoids, quercetin 3'-O-glucoside (5), and rutin (6). The volatile constituents of the plant flowers were analyzed for the first time by GC/MS, which led to the identification of 26 known compounds (Table 1). Finally, the antimicrobial activity of the petroleum ether extract of the flowers of H. littoralis was investigated.

MeSH terms

  • Amaryllidaceae Alkaloids / chemistry
  • Amaryllidaceae Alkaloids / isolation & purification
  • Amaryllidaceae Alkaloids / pharmacology*
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology
  • Dose-Response Relationship, Drug
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification
  • Flavonoids / pharmacology*
  • Flowers / chemistry
  • Glucosides
  • Magnoliopsida / chemistry*
  • Microbial Sensitivity Tests
  • Molecular Conformation
  • Phenanthridines / chemistry
  • Phenanthridines / isolation & purification
  • Phenanthridines / pharmacology*
  • Plant Roots / chemistry
  • Pseudomonas aeruginosa / drug effects
  • Quercetin / analogs & derivatives
  • Rutin / chemistry
  • Rutin / isolation & purification
  • Rutin / pharmacology*
  • Staphylococcus aureus / drug effects
  • Stereoisomerism
  • Structure-Activity Relationship

Substances

  • 11-hydroxyvittatine
  • 8-demethylmaritidine
  • Amaryllidaceae Alkaloids
  • Anti-Bacterial Agents
  • Flavonoids
  • Glucosides
  • Phenanthridines
  • quercetin 3'-O-glucoside
  • hippeastrine
  • Rutin
  • Quercetin
  • lycorine