A well-tolerated 5-FU-based treatment subsequent to severe capecitabine-induced toxicity in a DPD-deficient patient

Br J Clin Pharmacol. 2008 Jun;65(6):966-70. doi: 10.1111/j.1365-2125.2008.03106.x. Epub 2008 Feb 20.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antimetabolites, Antineoplastic / adverse effects*
  • Breast Neoplasms / drug therapy*
  • Capecitabine
  • Deoxycytidine / adverse effects
  • Deoxycytidine / analogs & derivatives*
  • Dihydropyrimidine Dehydrogenase Deficiency / genetics*
  • Drug Monitoring / methods
  • Female
  • Fluorouracil / adverse effects
  • Fluorouracil / analogs & derivatives*
  • Fluorouracil / therapeutic use*
  • Humans
  • Polymorphism, Genetic / genetics

Substances

  • Antimetabolites, Antineoplastic
  • Deoxycytidine
  • Capecitabine
  • Fluorouracil