Calmodulin-binding transcription activator (CAMTA) 3 mediates biotic defense responses in Arabidopsis

FEBS Lett. 2008 Mar 19;582(6):943-8. doi: 10.1016/j.febslet.2008.02.037. Epub 2008 Feb 25.

Abstract

Calmodulin-binding transcription activator (CAMTA) 3 (also called SR1) is a calmodulin-binding transcription factor in Arabidopsis. Two homozygous T-DNA insertion mutants (camta3-1, camta3-2) showed enhanced spontaneous lesions. Transcriptome analysis of both mutants revealed 6 genes with attenuated expression and 99 genes with elevated expression. Of the latter, 32 genes are related to defense against pathogens (e.g. WRKY33, PR1 and chitinase). Propagation of a virulent strain of the bacterial pathogen Pseudomonas syringae and the fungal pathogen Botrytis cinerea were attenuated in both mutants. Moreover, both mutants accumulated high levels of H2O2. We suggest that CAMTA3 regulates the expression of a set of genes involved in biotic defense responses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / genetics*
  • Arabidopsis / microbiology
  • Arabidopsis Proteins / genetics
  • Arabidopsis Proteins / metabolism*
  • Botrytis / growth & development
  • Calmodulin-Binding Proteins / genetics
  • Calmodulin-Binding Proteins / metabolism*
  • Gene Expression Profiling
  • Gene Expression Regulation, Plant*
  • Mutagenesis, Insertional
  • Plant Diseases / genetics*
  • Plant Diseases / microbiology
  • Pseudomonas syringae / growth & development
  • Reactive Oxygen Species / metabolism
  • Transcription Factors / genetics
  • Transcription Factors / metabolism*

Substances

  • Arabidopsis Proteins
  • Calmodulin-Binding Proteins
  • Reactive Oxygen Species
  • SR1 protein, Arabidopsis
  • Transcription Factors