Applications of poly(3,4-ethylenedioxythiophene) doped with poly(styrene sulfonic acid) transistors in chemical and biological sensors

Chem Rec. 2008;8(1):13-22. doi: 10.1002/tcr.20133.


The application of transistors based on poly(3,4-ethylenedioxythiophene) doped with poly(styrene sulfonic acid) (PEDOT:PSS) in chemical and biological sensing is reviewed. These devices offer enormous potential for facile processing of small, portable, and inexpensive sensors ideally suited for point-of-care analysis. They can be used to detect a wide range of analytes for a variety of possible applications in fields such as health care (medical diagnostics), environmental monitoring (airborne chemicals, water contamination, etc.), and food industry (smart packaging). Organic transistors are excellent candidates to act as transducers because they have the ability to translate chemical and biological signals into electronic signals with high sensitivity. Furthermore, fuctionalization of PEDOT:PSS films with a chemical or biological receptor can lead to high specificity. The advantages of using PEDOT:PSS transistors are described, and applications are presented for sensing analytes in both gaseous and aqueous environments.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Biosensing Techniques / instrumentation
  • Biosensing Techniques / methods*
  • Bridged Bicyclo Compounds, Heterocyclic / chemistry*
  • Electrochemistry
  • Environmental Monitoring
  • Microelectrodes
  • Polymers / chemistry*
  • Polystyrenes / chemistry*
  • Sensitivity and Specificity
  • Transistors, Electronic


  • Bridged Bicyclo Compounds, Heterocyclic
  • Polymers
  • Polystyrenes
  • poly(3,4-ethylene dioxythiophene)
  • polystyrene sulfonic acid