The first guaian-12-oic acid glucopyranosyl ester and other constituents from Picris rhagadioloides (L.) Desf. (Asteraceae)

Molecules. 2008 Feb 19;13(2):444-51. doi: 10.3390/molecules13020444.


The first guaian-12-oic acid glucopyranosyl ester was isolated from the roots of Picris rhagadioloides (L.) Desf. (Asteraceae), in addition to five costuslactone-type guaianolides, four germacranolides and three phenolic compounds. This is the first time that the known phenolics syringaldehyde and syringaresinol, as well as the known sesquiterpene lactones glucozaluzanin C, cichorioside C and hypochoeroside A have been described from a Picris species. The compounds were characterized on the basis of physicochemical, 1D- and 2D-NMR spectroscopic, and mass spectrometric data.

MeSH terms

  • Asteraceae / chemistry*
  • Carbon Isotopes
  • Cycloheptanes / chemistry*
  • Cycloheptanes / isolation & purification*
  • Glucosides / chemistry*
  • Glucosides / isolation & purification*
  • Magnetic Resonance Spectroscopy
  • Protons
  • Sesquiterpenes / chemistry*
  • Sesquiterpenes / isolation & purification*
  • Sesquiterpenes, Guaiane / chemistry*
  • Sesquiterpenes, Guaiane / isolation & purification*


  • 3-hydroxy-1,5,7H-guaia-4(15),10(14),11(13)-trien-12-oic acid glucopyranosyl ester
  • Carbon Isotopes
  • Cycloheptanes
  • Glucosides
  • Protons
  • Sesquiterpenes
  • Sesquiterpenes, Guaiane
  • guaiane