MNESIS: towards the integration of current multisystem models of memory

Neuropsychol Rev. 2008 Mar;18(1):53-69. doi: 10.1007/s11065-008-9052-3. Epub 2008 Feb 29.


After a brief description of the "diseases of memory" which have made the greatest contribution to theoretical developments in the past years, we turn our attention to the most important concepts to have arisen from the dissociations brought to light in different neuropsychological syndromes. This is followed by a critical review of the tasks currently used to assess each memory system. We then describe the monohierarchical model proposed by E. Tulving (Philos Trans R Soc Lond, B, Biol, Sci, 356:1505-1515, 2001), together with other recent concepts, notably Baddeley's model of working memory with its latest component, the episodic buffer. Lastly, we attempt to reconcile these models with several other theoretical propositions, which we have linked together in a macromodel--the Memory NEo-Structural Inter-Systemic model (MNESIS).

Publication types

  • Review

MeSH terms

  • Cognition / physiology
  • Humans
  • Memory / physiology*
  • Memory Disorders / physiopathology*
  • Memory Disorders / psychology*
  • Memory, Short-Term / physiology
  • Models, Psychological*
  • Psychomotor Performance / physiology