Effectiveness of the novel anti-diabetes medication exenatide in everyday practice: Comparison with clinical trials

Diabetes Res Clin Pract. 2008 May;80(2):e4-6. doi: 10.1016/j.diabres.2008.01.014. Epub 2008 Mar 7.


We evaluated effectiveness of exenatide in 81 unselected patients and compared the results with clinical trials. Patients achieved a similar reduction in A1C and lost more weight than patients in the clinical trials. Thirty-seven (46%) were treated off-label. Exenatide was effective on and off-label in this unselected patient group.

MeSH terms

  • Adult
  • Aged
  • Clinical Trials as Topic
  • Exenatide
  • Female
  • Humans
  • Hypoglycemic Agents / therapeutic use*
  • Male
  • Medical Records
  • Middle Aged
  • Peptides / therapeutic use*
  • Treatment Outcome
  • Venoms / therapeutic use*


  • Hypoglycemic Agents
  • Peptides
  • Venoms
  • Exenatide