Effects of a psychological intervention on depression in infertile couples

Int J Gynaecol Obstet. 2008 Jun;101(3):248-52. doi: 10.1016/j.ijgo.2007.12.010. Epub 2008 Mar 5.


Objective: To determine factors affecting depression in infertile couples and the impact of a psychological intervention before or during infertility treatment.

Methods: In a cross-sectional study with 638 infertile couples assessed for depression, 140 couples with a member who had a Beck Depression Inventory (BDI) score of 17 or higher were randomized to receive psychological treatment either before or during infertility treatment. Logistic regression was performed to eliminate confounding factors.

Results: Depression was initially found in 48% of women and 23.8% of men. The mean+/-SD Beck scores fell from 18.7+/-9.7 to 10.7+/-5.8 (P<0.001) in the group psychologically treated before they received infertility treatment.

Conclusion: The psychological intervention was found useful in alleviating depression in infertile couples before they received infertility treatment.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Anxiety / diagnosis
  • Anxiety / etiology
  • Anxiety / therapy*
  • Cognitive Behavioral Therapy*
  • Cross-Sectional Studies
  • Depression / diagnosis
  • Depression / etiology
  • Depression / therapy*
  • Female
  • Humans
  • Infertility / complications
  • Infertility / psychology*
  • Logistic Models
  • Male
  • Marriage / psychology
  • Sex Factors
  • Socioeconomic Factors
  • Stress, Psychological / etiology
  • Stress, Psychological / psychology
  • Stress, Psychological / therapy*