Sharp edge artifacts and spurious coupling in EEG frequency comodulation measures

J Neurosci Methods. 2008 May 30;170(2):352-7. doi: 10.1016/j.jneumeth.2008.01.020. Epub 2008 Feb 2.


Recent electroencephalogram (EEG), electrocorticogram (ECoG), and local field potential (LFP) observations suggest that distinct frequency bands interact. Numerous measures have been proposed to analyze such interactions, including the amplitude envelope modulation of high frequency activity by the phase or signal of low frequency activity. In this short communication, we describe how abrupt increases or decreases in voltage data may produce spurious coupling in these measures and suggest techniques to detect these effects.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Alpha Rhythm
  • Artifacts*
  • Computer Simulation
  • Data Interpretation, Statistical
  • Electroencephalography / statistics & numerical data*
  • Electrophysiology
  • Evoked Potentials / physiology
  • Software
  • Theta Rhythm