Sporadic bulbospinal muscle atrophy with facial-onset sensory neuropathy

Muscle Nerve. 2008 May;37(5):659-62. doi: 10.1002/mus.20991.


We report a case of idiopathic severe facial-onset sensorimotor neuropathy with no evidence of Kennedy's disease, familial amyotrophic lateral sclerosis, amyloidosis, Tangier disease, sarcoidosis, chronic basilar meningitis, or Sjögren's syndrome. Clinical and neurophysiological features of this patient resemble those of four recently reported patients who were affected with facial-onset sensorimotor neuropathy (FOSMN), a probably novel disease. The present report provides information about a further patient with FOSMN in order to better characterize the clinical and laboratory features of this disease.

Publication types

  • Case Reports

MeSH terms

  • Action Potentials / physiology
  • Facial Nerve Diseases / complications*
  • Humans
  • Male
  • Middle Aged
  • Muscular Atrophy, Spinal / complications*
  • Neural Conduction / physiology
  • Sensation Disorders / complications*