Minimization of potential hERG liability in histamine H3 receptor antagonists

Inflamm Res. 2008:57 Suppl 1:S45-6. doi: 10.1007/s00011-007-0622-2.
No abstract available

MeSH terms

  • Animals
  • Behavior, Animal
  • Benzofurans / chemistry
  • Cyclobutanes / chemistry
  • Histamine H3 Antagonists* / chemistry
  • Histamine H3 Antagonists* / metabolism
  • Humans
  • Male
  • Molecular Structure
  • Naphthalenes / chemistry
  • Radioligand Assay
  • Rats
  • Receptors, Histamine H3 / metabolism
  • Trans-Activators / genetics
  • Trans-Activators / metabolism*
  • Transcriptional Regulator ERG

Substances

  • Benzofurans
  • Cyclobutanes
  • ERG protein, human
  • Histamine H3 Antagonists
  • Naphthalenes
  • Receptors, Histamine H3
  • Trans-Activators
  • Transcriptional Regulator ERG
  • naphthalene
  • benzofuran