Physical activity, self-efficacy, and quality of life in multiple sclerosis

Ann Behav Med. 2008 Feb;35(1):111-5. doi: 10.1007/s12160-007-9006-7. Epub 2008 Feb 12.


Background: Quality of life (QOL) is compromised among individuals with multiple sclerosis (MS). Self-efficacy and physical activity have been positively associated with QOL in persons with MS, and based on a social cognitive perspective, the relationship between physical activity and QOL might be indirect and accounted for by self-efficacy.

Purpose: We tested the hypothesis that physical activity would be indirectly associated with QOL through a pathway that included self-efficacy.

Methods: Participants were 133 individuals with a definite diagnosis of MS who completed the Godin Leisure-Time Exercise Questionnaire, Multiple Sclerosis Self-Efficacy scale, and Multiple Sclerosis Impact Scale.

Results: Path analysis indicated that those with MS who were more physically active had greater self-efficacy for function and control, and self-efficacy for function and control were associated with greater physical and psychological components of QOL.

Conclusions: Our findings support physical activity as a possible modifiable behavior for mitigating reductions of QOL by improving self-efficacy in individuals with MS.

Publication types

  • Multicenter Study

MeSH terms

  • Adaptation, Psychological
  • Adult
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Motor Activity*
  • Multiple Sclerosis / classification
  • Multiple Sclerosis / psychology*
  • Quality of Life*
  • Self Efficacy*
  • Severity of Illness Index