[Non-healing iatrogenic gastric ulcers after endoscopic mucosal resection for gastric epithelial neoplasia: report of two cases]

Korean J Gastroenterol. 2008 Feb;51(2):127-31.
[Article in Korean]


Endoscopic mucosal resection (EMR) is widely accepted as a standard treatment for early gastric cancer or gastric adenoma. However, EMR inevitably results in the formation of large iatrogenic ulcer at the resected area. Although the characteristics of EMR-induced ulceration are not fully understood, this type of ulcer is thought to heal faster and to recur less often than non-iatrogenic gastric ulcer. Current available evidences have suggested that EMR-induced ulcers heal within 2-3 months. Herein, we report two cases of non-healing persistent gastric ulcers after EMR. One is a case of gastric carcinoma which developed at the same site of previous EMR site for the low grade dysplasia. The other is a case in which persistent EMR-induced ulcer was healed in the long run after Helicobacter pylori eradication therapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Endoscopy, Gastrointestinal
  • Gastric Mucosa / pathology
  • Gastric Mucosa / surgery*
  • Helicobacter Infections / complications
  • Helicobacter Infections / drug therapy
  • Helicobacter pylori
  • Humans
  • Iatrogenic Disease
  • Male
  • Middle Aged
  • Stomach Neoplasms / complications
  • Stomach Neoplasms / diagnosis
  • Stomach Neoplasms / surgery*
  • Stomach Ulcer / diagnosis
  • Stomach Ulcer / etiology*
  • Stomach Ulcer / pathology