The demographic profile of sero-discordant couples enrolled in clinical research in Rwanda and Zambia

AIDS Care. 2008 Mar;20(3):395-405. doi: 10.1080/09540120701593497.


This paper examines the demographic profile of two cohorts of sero-discordant couples enrolled in research activities at two clinical research sites in Kigali, Rwanda and Lusaka, Zambia and compares their background characteristics by country, gender and sero-status. Differences between the two cohorts represent economic and cultural differences between the two countries. Recruitment procedures appear to be successful in reaching the intended audience - couples from poor urban communities - and we suggest that similar recruitment strategies could be adopted to reach other population groups in other settings. The profiles of sero-discordant couples highlight several potential intervention points, and call for attention to be focused towards prevention efforts aimed at young women and their male partners.

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • AIDS Serodiagnosis / statistics & numerical data*
  • Adolescent
  • Adult
  • Attitude to Health*
  • Clinical Trials as Topic
  • Demography
  • Female
  • HIV Infections / epidemiology
  • HIV Infections / prevention & control*
  • Humans
  • Male
  • Middle Aged
  • Rwanda / epidemiology
  • Sexual Partners
  • Socioeconomic Factors
  • Zambia / epidemiology