Pseudotumor cerebri following tapered corticosteroid treatment in an 8-month-old infant

J Neurosurg Pediatr. 2008 Jan;1(1):88-90. doi: 10.3171/PED-08/01/088.

Abstract

The authors report on an 8-month-old infant with an orbital capillary hemangioma. The patient had been treated with high-dose corticosteroid therapy and had had a recent decrease in dose. The patient presented to the emergency department with increased irritability and bulging fontanelles. On lumbar puncture the opening pressure was > 55 cm H(2)O. Ophthalmological examination revealed interval development of papilledema. The child was treated with high-volume lumbar puncture, subsequent drainage of 10 ml of cerebrospinal fluid, resumption of the previous steroid dose, and acetazolomide therapy. The patient's symptoms resolved and follow-up ophthalmological examination revealed interval resolution of papilledema. The authors present the youngest reported case of pseudotumor development after corticosteroid tapering.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / adverse effects*
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Hemangioma, Capillary / drug therapy*
  • Hemangioma, Capillary / pathology*
  • Hemangioma, Capillary / surgery
  • Humans
  • Infant
  • Male
  • Neurosurgical Procedures / methods
  • Orbital Neoplasms / drug therapy*
  • Orbital Neoplasms / pathology*
  • Orbital Neoplasms / surgery
  • Papilledema / chemically induced
  • Pseudotumor Cerebri / chemically induced*
  • Suction

Substances

  • Anti-Inflammatory Agents