Asymptomatic gonorrhea and chlamydial infections detected by nucleic acid amplification tests among Boston area men who have sex with men

Sex Transm Dis. 2008 May;35(5):495-8. doi: 10.1097/OLQ.0b013e31816471ae.


Background: The purpose of this project was to determine the prevalence of asymptomatic sexually transmitted diseases (STDs) among men who have sex with men (MSM) in the Boston area who had been sexually active (oral and/or anal sex) with another male within the past year.

Methods: Over a 1-month period (March 2007), asymptomatic MSM in care at a Boston community health center (n = 114) were screened for gonorrhea and chlamydia using the BD ProbeTec technique. Deidentified medical record data were analyzed and linked to prevalence monitoring results.

Results: Eleven percent of the sample tested positive for one of the 2 STDs (gonorrhea or chlamydia) from at least one mucosal site. Individuals who were infected with an STD were considerably more likely to have a prior history of one or more STD infections when compared with those without an STD history (OR = 3.69; P <0.02). There were no significant differences observed in psychosocial and other behavioral risk factors between patients with or without an STD.

Conclusions: Screening asymptomatic MSM using nucleic acid amplification tests (NAATs) revealed a substantial STD burden that might not have been diagnosed using traditional assays. These data are critical for the design of effective public health interventions for this population.

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Chlamydia Infections / diagnosis
  • Chlamydia Infections / epidemiology*
  • Chlamydia Infections / etiology
  • Chlamydia Infections / prevention & control*
  • Chlamydia trachomatis / isolation & purification
  • Gonorrhea / diagnosis
  • Gonorrhea / epidemiology*
  • Gonorrhea / etiology
  • Gonorrhea / prevention & control*
  • Homosexuality, Male*
  • Humans
  • Male
  • Mass Screening
  • Massachusetts / epidemiology
  • Medical Records
  • Middle Aged
  • Neisseria gonorrhoeae / isolation & purification
  • Nucleic Acid Amplification Techniques
  • Predictive Value of Tests
  • Prevalence
  • Retrospective Studies
  • Urban Health