The scope of our study was to assess the prevalence of metabolic syndrome (MSy) and its components in the type 2 diabetic population with symptomatic coronary artery disease in a sample of the Macedonian population. 327 pts with type 2 diabetes and manifested coronary artery disease were randomly included in a survey. MSy was defined according ATP III criteria. The data presented a prevalence of MSy in 86.2%, respectively. 98% of pts had at least one more MSy component than impaired glycaemia. Study groups with four and three MSy components were most frequent in the study population. The data presented gender differences in MSy prevalence: 93.4% in women vs. 82.8% in men (p 0.009), as women tend to have a much more increased waist, arterial hypertension and low HDL. The most prevalent metabolic syndrome component was arterial hypertension (78.3%). Low HDL was detected in 67.9%, hypertriglicerydaemia in 62.7%, and an increased waist in 49.8% of the study population.