Resistance Training Conserves Fat-Free Mass and Resting Energy Expenditure Following Weight Loss

Obesity (Silver Spring). 2008 May;16(5):1045-51. doi: 10.1038/oby.2008.38. Epub 2008 Mar 6.

Abstract

Objective: To determine what effect diet-induced approximately 12 kg weight loss in combination with exercise training has on body composition and resting energy expenditure (REE) in premenopausal African-American (AA) and European-American (EA) women.

Methods and procedures: This study was a longitudinal, randomized weight loss clinical intervention, with either aerobic (AT), resistance (RT), or no exercise training (NT). Forty-eight AA and forty-six EA premenopausal overweight (BMI between 27 and 30) women underwent weight loss to a BMI<25. Body composition (densitometry), REE (indirect calorimetry), maximal oxygen uptake (VO2max), and muscular strength (isometric elbow flexion) were evaluated when subjects were in energy balance.

Results: AA women lost less fat-free mass (FFM, P<or=0.05) (47.0+/-4.6 to 46.9+/-5.0 kg) than EA women (46.4+/-4.9 to 45.2+/-4.6 kg). Regardless of race, RT maintained FFM (P<or=0.05) following weight loss (46.9+/-5.2 to 47.2+/-5.0 kg) whereas AT (45.4+/-4.2 to 44.4+/-4.1 kg) and NT (47.9+/-4.7 to 46.4+/-5.1 kg) decreased FFM (P<or=0.05). Both AT and NT decreased in REE with weight loss but RT did not. Significant time by group interactions (all P<or=0.05) for strength indicated that RT maintained strength and AT did not.

Discussion: AA women lost less FFM than EA women during equivalent weight losses. However, following weight loss in both AA and EA, RT conserved FFM, REE, and strength fitness when compared to women who AT or did not train.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • African Americans
  • Body Composition / physiology*
  • Body Mass Index
  • Body Weight / physiology
  • Combined Modality Therapy
  • Diet, Reducing*
  • Energy Metabolism / physiology*
  • European Continental Ancestry Group
  • Exercise / physiology*
  • Female
  • Humans
  • Longitudinal Studies
  • Muscle Strength / physiology
  • Obesity / ethnology
  • Obesity / physiopathology
  • Obesity / therapy*
  • Oxygen Consumption / physiology
  • Physical Fitness / physiology
  • Rest / physiology*
  • Weight Loss / physiology*