Phytochemical investigation on leaf extract of Cordia salicifolia Cham

J Med Food. 2008 Mar;11(1):193-4. doi: 10.1089/jmf.2007.583.


The dichloromethane extract of leaves of Cordia salicifolia Cham. (Family Boraginaceae) was fractionated by SiO(2) column chromatography and analyzed by gas chromatography, gas chromatography-mass spectrometry, and nuclear magnetic resonance spectroscopy. The apolar extract is characterized by a very high content of (+)-spathulenol (0.53%). The major component of the extract exhibited a very weak activity as an inhibitor of growth of Helicobacter pylori in vitro (minimum inhibitory concentration = 200 microg/mL).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chemical Fractionation
  • Chromatography, Gas
  • Cordia / chemistry*
  • Gas Chromatography-Mass Spectrometry
  • Helicobacter pylori / drug effects
  • Helicobacter pylori / growth & development
  • Magnetic Resonance Spectroscopy
  • Methylene Chloride
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology
  • Plant Leaves / chemistry*
  • Sesquiterpenes / analysis


  • Plant Extracts
  • Sesquiterpenes
  • Methylene Chloride
  • spathulenol