Infectious intracranial aneurysms in the pediatric population: endovascular treatment with Onyx

Childs Nerv Syst. 2008 Aug;24(8):909-15. doi: 10.1007/s00381-008-0614-8. Epub 2008 Mar 26.


Objects: Infectious intracranial aneurysms present a treatment challenge in the pediatric population. Current endovascular strategies and tools have been developed, which make treatment of infectious intracranial aneurysms with liquid embolics safe and effective. This study reviews the use of the liquid embolic Onyx in the treatment of infectious intracranial aneurysms in the pediatric population.

Materials and methods: We used an endovascular approach to treat ruptured infectious intracranial aneurysms. We embolized the aneurysms with either Onyx alone or in combination with platinum coils.

Conclusion: Endovascular therapy with liquid embolics (Onyx) has been shown to be a safe and effectual treatment option in the case of pediatric infectious intracranial aneurysms. The combination of endovascular modalities can also be used to tailor the therapeutic goal of exclusion of infectious aneurysms with good results. Further studies are needed to assess the long-term effectiveness of this approach to pediatric infectious intracranial aneurysms.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Age Factors
  • Aneurysm, Infected / etiology
  • Aneurysm, Infected / therapy*
  • Aneurysm, Ruptured / therapy*
  • Cerebral Angiography
  • Cerebral Arteries / pathology
  • Cerebral Arteries / surgery
  • Dimethyl Sulfoxide / therapeutic use*
  • Embolism / chemically induced
  • Embolization, Therapeutic / methods*
  • Endocarditis, Bacterial / complications
  • Female
  • Humans
  • Infant, Newborn
  • Intracranial Aneurysm / therapy*
  • Neurosurgical Procedures / methods
  • Polyvinyls / therapeutic use*
  • Stents
  • Treatment Outcome


  • Onyx copolymer
  • Polyvinyls
  • Dimethyl Sulfoxide