Acute laryngeal and bronchial obstruction after CS (o-chlorobenzylidenemalononitrile) gas inhalation

Eur Arch Otorhinolaryngol. 2009 Feb;266(2):301-4. doi: 10.1007/s00405-008-0653-5. Epub 2008 Mar 26.


CS gas (o-chlorobenzylidenemalononitrile) is one of the most commonly used riot agents. It can create excessive tearing, conjunctivitis, uncontrolled blinking (blepharospasm) and a sensation of burning and pain at initial exposure. Pulmonary edema (ARDS) and/or diffuse airway lesions on human would be lethal after CS inhalation. We report a case with acute laryngeal and bronchial obstruction due to vocal cord edema and extensive crusting at glottic level, trachea and bronchi. The CS gas was sprayed in a 6 x 6 m(2) closed room, and she was exposed to increased concentration of the gas for 10 s. Surprisingly, her initial symptoms were raised 21 days after CS spray exposure.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Administration, Inhalation
  • Adolescent
  • Airway Obstruction / chemically induced*
  • Airway Obstruction / physiopathology
  • Airway Obstruction / therapy
  • Bronchoscopy
  • Combined Modality Therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Laryngeal Edema / chemically induced*
  • Laryngeal Edema / diagnosis
  • Laryngeal Edema / therapy
  • Laryngoscopy
  • Riot Control Agents, Chemical / administration & dosage
  • Riot Control Agents, Chemical / adverse effects*
  • Risk Assessment
  • Severity of Illness Index
  • Tracheostomy / methods
  • o-Chlorobenzylidenemalonitrile / adverse effects*
  • o-Chlorobenzylidenemalonitrile / chemistry


  • Riot Control Agents, Chemical
  • o-Chlorobenzylidenemalonitrile