The potential effect of statins on rituximab immunotherapy

PLoS Med. 2008 Mar 25;5(3):e77. doi: 10.1371/journal.pmed.0050077.

Abstract

The author discusses a new study showing that statins have an inhibitory effect upon rituximab treatment.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Antibodies, Monoclonal / metabolism
  • Antibodies, Monoclonal / therapeutic use*
  • Antibodies, Monoclonal, Murine-Derived
  • Antibody-Dependent Cell Cytotoxicity / drug effects
  • Contraindications
  • Cytotoxicity, Immunologic / drug effects
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors* / adverse effects
  • Lymphoma, B-Cell / drug therapy
  • Rituximab

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Murine-Derived
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Rituximab