Substance P receptor-expressing dorsal horn neurons: lessons from the targeted cytotoxin, substance P-saporin

Pain. 2008 May;136(1-2):7-10. doi: 10.1016/j.pain.2008.03.010. Epub 2008 Mar 26.

Author

Ronald G Wiley¹

Affiliation

¹ Laboratory of Experimental Neurology, Neurology Service, VA TVHS, 1310 24th Avenue, South Nashville, TN 37212-2637, USA. ronald.wiley@vanderbilt.edu

PMID: 18372112
DOI: 10.1016/j.pain.2008.03.010

No abstract available

Publication types

Review

MeSH terms

Animals
Gene Expression Regulation / drug effects
Gene Expression Regulation / physiology*
Humans
Immunotoxins / metabolism
Immunotoxins / toxicity
Pain / chemically induced
Pain / genetics
Pain / metabolism
Posterior Horn Cells / drug effects
Posterior Horn Cells / pathology*
Receptors, Neurokinin-1 / biosynthesis*
Receptors, Neurokinin-1 / genetics
Receptors, Neurokinin-1 / physiology
Ribosome Inactivating Proteins, Type 1 / physiology
Ribosome Inactivating Proteins, Type 1 / toxicity*
Saporins
Substance P / analogs & derivatives*
Substance P / physiology
Substance P / toxicity

Substances

Immunotoxins
Receptors, Neurokinin-1
Ribosome Inactivating Proteins, Type 1
substance P-saporin
Substance P
Saporins