MRSA infection in lower extremity wounds

Int J Low Extrem Wounds. 2008 Mar;7(1):28-31. doi: 10.1177/1534734608314090.


Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most frequently isolated bacteria in wound cultures. MRSA has been linked to lengthened wound healing times, an increase in adverse postoperative outcomes, and mortality. This study investigated the incidence of MRSA in lower extremity wounds and examined outcomes associated with MRSA-infected wounds versus non-MRSA-infected wounds. A retrospective study was conducted. Patients with MRSA-infected wounds were compared with those with uninfected wounds in a 1:2 ratio. Demographics, infection, and stay information were collected. Data were analyzed using SPSS 15.0. 51 patients were included (17 with MRSA and 34 without MRSA). Patients with MRSA had increased lengths of stay and a higher incidence of adverse postoperative outcomes compared with non-MRSA patients. An MRSA infection adversely affects a patient's hospital course. Preoperative screening for MRSA and postoperative surveillance should be considered to prevent and eliminate the spread of this virulent bacterium.

MeSH terms

  • Female
  • Humans
  • Leg Injuries / drug therapy
  • Leg Injuries / microbiology*
  • Length of Stay
  • Male
  • Methicillin Resistance*
  • Retrospective Studies
  • Risk Factors
  • Staphylococcal Infections / drug therapy*
  • Treatment Outcome
  • Wound Infection / drug therapy*