Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Filters applied. Clear all
Review
. 2008;78:435-42.
doi: 10.1016/S0083-6729(07)00018-0.

Hepatocellular Carcinoma and Vitamin K

Affiliations
Review

Hepatocellular Carcinoma and Vitamin K

Toshihiko Mizuta et al. Vitam Horm. .

Abstract

On the basis of reports of the antitumor effects of vitamin K on various cancers, we clinically investigated the suppressive effects of vitamin K2 on tumor recurrence after curative treatment for hepatocellular carcinoma (HCC). Our results showed that vitamin K2 administration significantly suppressed HCC recurrence. Our laboratory findings revealed that the inhibitory effect of vitamin K2 against HCC cell growth was generated by suppressing cyclin D1 expression through inhibition of NF-kappaB activation.

Similar articles

See all similar articles

Cited by 5 articles

MeSH terms

LinkOut - more resources

Feedback