[Heart involvement in patients with multiple myeloma based on echocardiographic data]

Vrach Delo. 1991 Jul:(7):49-53.
[Article in Russian]


An echocardiographic study of 50 patients with multiple myeloma was carried out. Disorders of the contractile and pumping function of the left ventricle myocardium, changes of the central hemodynamics were revealed. It was shown that at stage I the main functions of the heart are maintained due to myocardial hypertrophy. Progression of the disease, development of chronic renal failure and concomitant pathology of the cardiovascular system, the contractile function of the myocardium is essentially reduced, the left ventricle and left atrium is dilated. It is concluded that echocardiography allows to reveal early sings of cardiac lesions and predict development of cardiac insufficiency.

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cardiomegaly / diagnostic imaging
  • Cardiomegaly / etiology
  • Cardiomegaly / physiopathology
  • Chronic Disease
  • Echocardiography*
  • Female
  • Heart Failure / diagnostic imaging*
  • Heart Failure / etiology
  • Heart Failure / physiopathology
  • Hemodynamics
  • Humans
  • Male
  • Middle Aged
  • Multiple Myeloma / complications
  • Multiple Myeloma / diagnostic imaging*
  • Multiple Myeloma / drug therapy
  • Multiple Myeloma / physiopathology