[Complex influence of chemo- and ozonotherapy on the immunity of patients with destructive pulmonary tuberculosis]

Probl Tuberk Bolezn Legk. 2008:(2):20-3.
[Article in Russian]


The impact of standardized antimycobacterial treatment versus a complex combination of chemo- and ozonotherapy on the T and B links and specific antituberculous immunity was studied in patients with destructive pulmonary tuberculosis. A course of ozonotherapy was performed in the early intensive phase of antimycobacterial therapy via endovascular injection of ozonized 0.9% NaCl solution. Ozonotherapy used in the early intensive phase of the standardized treatment in patients with destructive pulmonary tuberculosis results in normalization of the count of tuberculin-sensitized T cells and the number of PPD-L proliferating lymphocytes, promotes decreased tuberculin sensitivity, accelerates normalization of humoral immunity (IgM, IgE), and activates the proliferative capacity of T cells in the early periods.

Publication types

  • English Abstract

MeSH terms

  • Antibiotics, Antitubercular / therapeutic use*
  • Drug Therapy, Combination
  • Humans
  • Immunoglobulin A / immunology
  • Immunoglobulin G / immunology
  • Immunoglobulin M / immunology
  • Injections, Intravenous
  • Ozone / administration & dosage
  • Ozone / therapeutic use*
  • Tuberculosis, Pulmonary / drug therapy
  • Tuberculosis, Pulmonary / immunology
  • Tuberculosis, Pulmonary / therapy*


  • Antibiotics, Antitubercular
  • Immunoglobulin A
  • Immunoglobulin G
  • Immunoglobulin M
  • Ozone