[Spinal cord ischaemia and preoperative clopidogrel withdrawal in an arteriosclerotic patient]

O Murat; E Durand; G Delépine; P Nguyen; J-M Malinovsky

doi:10.1016/j.annfar.2008.01.026

[Spinal cord ischaemia and preoperative clopidogrel withdrawal in an arteriosclerotic patient]

Ann Fr Anesth Reanim. 2008 Apr;27(4):335-7. doi: 10.1016/j.annfar.2008.01.026. Epub 2008 Apr 2.

[Article in French]

Authors

O Murat¹, E Durand, G Delépine, P Nguyen, J-M Malinovsky

Affiliation

¹ Département d'anesthésie réanimation, hôpital Robert-Debré, rue Alexis Carrel, 51092 Reims, France.

PMID: 18378112
DOI: 10.1016/j.annfar.2008.01.026

Abstract

We report the case of a motor impairment associated with bladder dysfunction several days after clopidogrel withdrawal in an arteriosclerotic woman scheduled for thoracotomy under general and thoracic epidural anaesthesia. Even if spinal artery syndrome may have a lot of aetiologies, we believe in a direct link between clopidogrel withdrawal and medulla ischaemia.

Publication types

Case Reports

MeSH terms

Arteriosclerosis / drug therapy
Clopidogrel
Female
Humans
Middle Aged
Platelet Aggregation Inhibitors / adverse effects*
Spinal Cord Ischemia / chemically induced*
Substance Withdrawal Syndrome*
Ticlopidine / adverse effects
Ticlopidine / analogs & derivatives*

Substances

Platelet Aggregation Inhibitors
Clopidogrel
Ticlopidine