Abstract
One-pot synthesis of various 2,3-polymethylene-4(3H)-quinazolinones from anthranilic acid, corresponding lactam and SOCl(2) is described, which can be applicable to the synthesis of simple 4(3H)-quinazolinone-derived alkaloids, such as luotonin A, tryptanthrin, and rutaecarpine.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Chemical Phenomena
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Chemistry, Physical
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Indicators and Reagents
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Indole Alkaloids / chemical synthesis*
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Lactams / chemical synthesis
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Magnetic Resonance Spectroscopy
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Pyrroles / chemical synthesis*
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Quinazolines / chemical synthesis*
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Quinazolinones / chemical synthesis*
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Quinones / chemical synthesis*
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Spectrophotometry, Infrared
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ortho-Aminobenzoates / chemistry
Substances
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Indicators and Reagents
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Indole Alkaloids
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Lactams
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Pyrroles
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Quinazolines
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Quinazolinones
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Quinones
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luotonin A
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ortho-Aminobenzoates
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anthranilic acid
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tryptanthrine
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rutecarpine