Frosted branch angiitis associated with Epstein-Barr virus systemic infection

Ocul Immunol Inflamm. 2008 Jan-Feb;16(1):41-3. doi: 10.1080/09273940701799114.

Abstract

Purpose: To describe the first case that the authors are aware of frosted branch angiitis associated with Epstein-Barr virus infection.

Methods: Case report.

Results: A 7-year-old boy presented with bilateral decreased visual acuity. Funduscopy showed a typical image of frosted branch angiitis. He was started on treatment with intravenous steroids and acyclovir. Serological testing was positive for anti-Epstein-Barr virus IgM antibodies. Anti-Epstein-Barr virus IgG antibodies tested positive later. During follow-up, the venous sheathing decreased. Three months later funduscopy showed no abnormalities.

Conclusion: Epstein-Barr virus infection should be considered in patients presenting with the typical clinical manifestations of this syndrome.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / therapeutic use
  • Administration, Oral
  • Antiviral Agents / therapeutic use
  • Child
  • Epstein-Barr Virus Infections* / drug therapy
  • Fundus Oculi
  • Humans
  • Male
  • Steroids / administration & dosage
  • Steroids / therapeutic use
  • Tomography, Optical Coherence
  • Vasculitis / diagnosis*
  • Vasculitis / drug therapy
  • Vasculitis / pathology
  • Vasculitis / virology*

Substances

  • Antiviral Agents
  • Steroids
  • Acyclovir