Fast and easy treatment for reduction of the Tyndall effect secondary to cosmetic use of hyaluronic acid

J Drugs Dermatol. 2008 Mar;7(3):281-3.


The use of hyaluronic acid (HA) filler substances for facial skin wrinkling and volume loss has become popular. With increasing use, physicians are likely to encounter side effects. One such side effect is a bluish discoloration known as the Tyndall effect. Recently, we have encountered a few cases in which patients presented with a bluish tint in the areas where hyaluronic acid was injected. A number of treatments can be performed to reverse these unwanted effects. We present a simple method for correction of misplacement of HA gel.

Publication types

  • Case Reports

MeSH terms

  • Cosmetic Techniques / adverse effects*
  • Female
  • Humans
  • Hyaluronic Acid / administration & dosage
  • Hyaluronic Acid / adverse effects*
  • Injections, Intradermal
  • Lip / pathology
  • Middle Aged
  • Pigmentation Disorders / etiology*
  • Pigmentation Disorders / pathology
  • Pigmentation Disorders / therapy*
  • Skin / pathology
  • Skin Aging*


  • Hyaluronic Acid