A population-based study of the incidence of complications associated with type 2 diabetes in the elderly

Diabet Med. 1991 Dec;8(10):928-33. doi: 10.1111/j.1464-5491.1991.tb01532.x.

Abstract

One hundred and eighty-eight known Type 2 diabetic patients aged over 60 years identified by a geographically based survey of a population of 40,076 were followed for a median of 6 years to determine the incidence of various complications. There were 63 deaths and two patients were lost to follow-up. The presence of complications was determined using a structured questionnaire and clinical examination. Incidence rates of ischaemic heart disease, stroke, and peripheral vascular disease (PVD) were 56 (95% CI 41-75), 22 (13-35), and 146 (117-174) 1000-person-years-1 of follow-up, respectively. Rates of stroke and PVD rose significantly with age. Retinopathy occurred at a rate of 60 (42-83) 1000-person-years-1 and cataract at 29 (17-46) 1000-person-years-1 although visual acuity in survivors did not deteriorate overall, probably reflecting the high mortality associated with cataract. The rate of proteinuria (albumin concentration greater than 300 mg l-1) was 19 (9-34) 1000-person-years-1. Incidence rates were unrelated to sex or duration of diabetes. Diabetes is associated with a continuing incidence of complications into old age. Adequate facilities are required to assess and treat the resulting morbidity in a population with an increasing proportion of elderly people.

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Cataract / epidemiology
  • Cerebrovascular Disorders / epidemiology
  • Coronary Disease / epidemiology
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / mortality
  • Diabetes Mellitus, Type 2 / physiopathology*
  • Diabetic Angiopathies / epidemiology*
  • Diabetic Nephropathies / epidemiology*
  • Diabetic Retinopathy / epidemiology*
  • England / epidemiology
  • Female
  • Follow-Up Studies
  • Foot Ulcer / epidemiology
  • Humans
  • Hypertension / epidemiology
  • Incidence
  • Male
  • Middle Aged
  • Vascular Diseases / epidemiology
  • Vision Disorders / epidemiology
  • Visual Acuity