Abstract
A previously healthy male with subacute onset right leg weakness was suspected to have an astrocytoma as imaging showed a lesion. Subsequent biopsy showed the presence of foamy macrophages containing periodic acid-Schiff staining granules, suggesting Whipple disease as a possible diagnosis.
MeSH terms
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Anti-Bacterial Agents / therapeutic use
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Ceftriaxone / therapeutic use
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Drug Therapy, Combination
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Duodenum
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Foam Cells / pathology
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Humans
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Periodic Acid-Schiff Reaction
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Recurrence
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Spinal Diseases / drug therapy
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Spinal Diseases / microbiology
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Spinal Diseases / pathology*
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Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use
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Tropheryma / isolation & purification
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Whipple Disease / drug therapy
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Whipple Disease / microbiology
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Whipple Disease / pathology*
Substances
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Anti-Bacterial Agents
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Ceftriaxone
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Trimethoprim, Sulfamethoxazole Drug Combination