Causes of corneal blindness: a multi-center retrospective review

J Med Assoc Thai. 2007 Dec;90(12):2651-7.


Objective: To assess prevalence and causes of corneal blindness in four hospitals in Thailand and to compare the causes between hospitals.

Material and method: A retrospective chart review of six hundred and sixty four patients records with best-corrected visual acuity not better than 6/60 in at least one eye due to corneal disease in Siriraj, Mettapracharak, Sappasitthiprasong and Banmee Hospitals in a one-year period were reviewed. The collected data included age, sex, laterality, causes of corneal blindness, and prognosis.

Results: Seven hundred and sixty nine eyes with corneal blindness and a median age of 55.0 years were reviewed Leading causes of cornea blindness were corneal infection (35.6%), surgical bullous keratopathy (27.8%), and trauma (14.0%). The prevalence at Siriraj Hospital was 1.7% (498/28,728 patients). Most of the treatable cases (84.6%) underwent penetrating keratoplasty procedures and 73% of patients had a chance of recovery.

Conclusion: Corneal infection and surgical bullous keratopathy were the leading causes of corneal blindness.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Blindness / epidemiology
  • Blindness / etiology*
  • Blindness / physiopathology
  • Child
  • Child, Preschool
  • Corneal Diseases / epidemiology
  • Corneal Diseases / etiology*
  • Corneal Diseases / physiopathology
  • Corneal Opacity / complications*
  • Eye Infections / complications*
  • Female
  • Hospitals, Public
  • Humans
  • Infant
  • Keratoplasty, Penetrating / adverse effects*
  • Male
  • Middle Aged
  • Prevalence
  • Retrospective Studies
  • Risk Factors
  • Thailand / epidemiology