The influence of porous silicon on axonal outgrowth in vitro

IEEE Trans Biomed Eng. 2008 Apr;55(4):1447-9. doi: 10.1109/TBME.2007.912423.

Abstract

xonal outgrowth on smooth and porous silicon surfaces was studied in organ culture. The pore size of the silicon substrata varied between 100 and 1500 nm. We found that axons preferred to grow and elongate on porous silicon surfaces only when pores of (150-500 nm) are available.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Axons / physiology*
  • Axons / ultrastructure*
  • Biocompatible Materials / chemistry*
  • Cell Enlargement
  • Cells, Cultured
  • Female
  • Ganglia, Spinal / cytology
  • Ganglia, Spinal / growth & development
  • Materials Testing
  • Mice
  • Porosity
  • Posterior Horn Cells / cytology*
  • Posterior Horn Cells / growth & development*
  • Silicon / chemistry*

Substances

  • Biocompatible Materials
  • Silicon