Theoretical analysis of reverse-time correlation for idealized orientation tuning dynamics

J Comput Neurosci. 2008 Dec;25(3):401-38. doi: 10.1007/s10827-008-0085-7. Epub 2008 Apr 8.


A theoretical analysis is presented of a reverse-time correlation method used in experimentally investigating orientation tuning dynamics of neurons in the primary visual cortex. An exact mathematical characterization of the method is developed, and its connection with the Volterra-Wiener nonlinear systems theory is described. Various mathematical consequences and possible physiological implications of this analysis are illustrated using exactly solvable idealized models of orientation tuning.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Humans
  • Mathematics
  • Models, Neurological*
  • Nonlinear Dynamics*
  • Orientation / physiology*
  • Photic Stimulation / methods
  • Sensory Receptor Cells / physiology*
  • Time Factors
  • Visual Cortex / cytology*
  • Visual Cortex / physiology