Single Nucleotide Polymorphism Typing of Bacillus Anthracis From Sverdlovsk Tissue

Emerg Infect Dis. 2008 Apr;14(4):653-6. doi: 10.3201/eid1404.070984.

Abstract

A small number of conserved canonical single nucleotide polymorphisms (canSNP) that define major phylogenetic branches for Bacillus anthracis were used to place a Sverdlovsk patient's B. anthracis genotype into 1 of 12 subgroups. Reconstruction of the pagA gene also showed a unique SNP that defines a new lineage for B. anthracis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anthrax / epidemiology*
  • Anthrax / microbiology
  • Antigens, Bacterial / genetics
  • Bacillus anthracis / classification*
  • Bacillus anthracis / genetics*
  • Bacterial Proteins / genetics
  • Bacterial Toxins / genetics
  • DNA, Bacterial / chemistry
  • Genotype
  • Humans
  • Inhalation Exposure
  • Phylogeny
  • Polymorphism, Single Nucleotide*
  • Russia / epidemiology

Substances

  • Antigens, Bacterial
  • Bacterial Proteins
  • Bacterial Toxins
  • DNA, Bacterial
  • anthrax toxin