Abstract
The total synthesis of 8a-epi-swainsonine has been achieved in 20% overall yield from R-glyceraldehyde dimethylacetonide 3 through epoxidation with the achiral furyl-substituted sulfonium ylide 2d as one of the key steps.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aldehydes / chemistry
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Catalysis
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Molecular Structure
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Stereoisomerism
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Sulfur Compounds / chemistry*
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Swainsonine / chemical synthesis*
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Swainsonine / chemistry
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Thiophenes / chemistry
Substances
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Aldehydes
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Sulfur Compounds
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Thiophenes
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tetrahydrothiophene
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Swainsonine