High risk strategy in smoking cessation is feasible on a population-based level. The Inter99 study

Prev Med. 2008 Jun;46(6):579-84. doi: 10.1016/j.ypmed.2008.02.026. Epub 2008 Mar 10.


Introduction: A high risk strategy is one of more strategies in public health. Smoking remains the most important contributor to the burden of disease in developed countries.

Methods: A population-based multi-factorial intervention study, Inter99 (1999-2006), Copenhagen, Denmark, using a high risk strategy. All 2408 daily smokers were repeatedly offered individual face-to-face lifestyle counselling. Smokers in the high-intensity group were offered participation in smoking cessation groups. We measured point abstinence at 1, 3 and 5-year follow-up and compared with a control group, using adjusted intention-to treat analyses.

Results: Compared with the control group it was twice as likely to be self-reported abstinent at 5-year follow-up in the high-intensity intervention group (OR: 2.19; 95%CI: 1.7-2.8; p<0.001). The effect of the intervention was significant, even when comparing validated abstinence in the intervention groups with self-reported abstinence in the control group (OR: 1.38; 95%CI: 1.1-1.8; p=0.014). Male gender, vocational training, higher age at onset of smoking, high knowledge of harm of smoking and lower tobacco consumption predicted abstinence.

Conclusion: A high risk strategy showed a significant effect on smoking in the long term. Proactive recruitment, face-to-face setting, repeated offer of assistance to quit and a multi-factorial approach may explain the success of the intervention.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Denmark
  • Directive Counseling
  • Feasibility Studies
  • Female
  • Health Status Indicators
  • Humans
  • Male
  • Middle Aged
  • Risk Assessment
  • Risk Factors
  • Smoking Cessation / methods*
  • Treatment Outcome