Budding and cell polarity in Saccharomyces cerevisiae

Curr Opin Genet Dev. 1991 Oct;1(3):342-50. doi: 10.1016/s0959-437x(05)80298-9.

Abstract

Budding by yeast follows a sequence of three stages. These include selection of a non-random bud-site, organization of that site and establishment of an associated axis of cytoskeletal polarity, and localized growth of the cell surface to produce the bud. Numerous components involved in each stage have been identified. As some of these components have close homologs in other organisms, there may exist common mechanisms involved in the establishment of cell polarity.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animal Population Groups / genetics
  • Animals
  • Fungal Proteins / genetics
  • Fungal Proteins / metabolism
  • GTP-Binding Proteins / genetics
  • GTP-Binding Proteins / metabolism
  • Gene Expression Regulation, Fungal*
  • Genes, Fungal
  • Mating Factor
  • Models, Biological
  • Morphogenesis / genetics
  • Peptides / genetics
  • Peptides / metabolism
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / growth & development*
  • Saccharomyces cerevisiae / ultrastructure
  • Signal Transduction

Substances

  • Fungal Proteins
  • Peptides
  • Mating Factor
  • GTP-Binding Proteins