The aim of our study is to evaluate Burnout syndrome in workers of a city in Southern Italy. The study was conducted on a sample of 1779 subjects including (562 teachers, 476 care worker, 549 employees) operating from birth and residents in the province of Messina. The data and clinic information were taken during the health surveillance. All subjects were administered during the health surveillance testing Maslach Burnout Inventory (M.B.I.). The category of Teachers presents 114 (20%) subjects with the syndrome. The category of care worker 74 cases (15.5%), the category of employees presents 83 cases (15.1%). It can be said that today the class teacher is more affected than the others as witnessed by the scientific literature.