Abstract
The investigation has shown that solutions of hydroxyethyl starch included in complex infusion therapy facilitate stabilization of hemodynamics in neurosurgical patients during surgery. Refortan exerts a more pronounced effect on the indices of hemodynamics as compared with voluven, but its modifying action on the hemostasis system is also more pronounced. These medicines used in doses 6-8 ml/kg fail to have substantial effects on efficiency of hemostasis in the brain wound and do not increase risk of postoperative hemorrhagic complications.
Publication types
-
Comparative Study
-
English Abstract
MeSH terms
-
Anesthesia / methods*
-
Hemodynamics / drug effects*
-
Homeostasis / drug effects*
-
Humans
-
Hydroxyethyl Starch Derivatives / administration & dosage*
-
Infusions, Intravenous
-
Intraoperative Care / methods
-
Middle Aged
-
Nervous System Diseases / physiopathology
-
Nervous System Diseases / surgery
-
Neurosurgical Procedures / methods*
-
Phenoxyacetates / administration & dosage*
-
Plasma Substitutes / administration & dosage*
Substances
-
HES 130-0.4
-
Hydroxyethyl Starch Derivatives
-
Phenoxyacetates
-
Plasma Substitutes
-
refortan