Community-acquired methicillin-resistant Staphylococcus aureus as a cause of Fournier's gangrene

Am J Med Sci. 2008 Apr;335(4):327-8. doi: 10.1097/MAJ.0b013e318142b7b9.


Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has become an important pathogen in aggressive skin and soft-tissue infections in patients without risk factors for nosocomial infections. We describe a case of a previously healthy adult who developed fulminant sepsis from Fournier's gangrene caused by a strain of CA-MRSA containing the Panton-Valentine leukocidin genes.

Publication types

  • Case Reports

MeSH terms

  • Bacterial Toxins / genetics
  • Community-Acquired Infections / complications*
  • Exotoxins / genetics
  • Fournier Gangrene / etiology*
  • Humans
  • Leukocidins / genetics
  • Male
  • Methicillin Resistance*
  • Middle Aged
  • Staphylococcal Infections / complications*


  • Bacterial Toxins
  • Exotoxins
  • Leukocidins
  • Panton-Valentine leukocidin