Seminal fructose and acid phosphatase levels have been determined in 30 vasectomised and 30 nonvasectomised healthy adults, both the groups being closely matched for age (32 to 45 years). The fructose and acid phosphatase values in the vasectomised men, 3 to 6 months after the operation, were 316 +/- 36 mg% and 2,098 +/- 112 K.A. units/ml, respectively, while in the control group they were 251 +/- 28 mg% and 1,932 +/- 92 K.A. units/ml. The differences are statistically significant (P less than 0.001) and the possible implications of the post-vasectomy rise in these androgen dependent seminal constituents are discussed.
PIP: Seminal fructose and acid phosphatase were determined in 30 men vasectomized 3-6 months before and in 30 age-matched controls, 32-45 years old. Each subject was tested twice and the values averaged, after 5 days of abstinence. Fructose levels averaged 316 mg% in vasectomized and 251 mg% in controls, by the Mann resorcinol and HCl method. Acid phosphatase activities were 2098 and 1932 King-Armstrong units/ml in vasectomized and in control men. Both values differed at the p less than .001 level, and were considered to be possibly related to Leydig cell hyperplasia.