Role of probiotic therapy in IBD

Inflamm Bowel Dis. 2008 Nov;14(11):1597-605. doi: 10.1002/ibd.20465.


There is mounting evidence that probiotic therapy may alter disease expression in both animal models of IBD and in patients with IBD. The effects appear to be modest at best and may reflect the choice of probiotic organism, the variability in concentrations of organisms administered, and the variability of the diseases being treated. This review examines the data of all fully published articles currently available for the role of probiotics in the treatment of IBD.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Colitis, Ulcerative / diagnosis
  • Colitis, Ulcerative / therapy*
  • Crohn Disease / diagnosis
  • Crohn Disease / therapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Inflammatory Bowel Diseases / diagnosis
  • Inflammatory Bowel Diseases / therapy
  • Male
  • Pouchitis / microbiology
  • Pouchitis / prevention & control*
  • Probiotics / therapeutic use*
  • Randomized Controlled Trials as Topic
  • Remission Induction / methods
  • Risk Assessment
  • Sensitivity and Specificity
  • Treatment Outcome