Adenosquamous carcinoma of the prostate: a case report

Hum Pathol. 1991 Oct;22(10):1046-50. doi: 10.1016/0046-8177(91)90014-g.


Mixed types of carcinoma of the prostate are rare. The majority of those described (22 cases) are examples of mixed adenocarcinoma and transitional cell carcinoma. Much more unusual is the mixed adenosquamous carcinoma, of which only three cases have been described. This report presents an additional case of the rare adenosquamous carcinoma of the prostate. It discusses the clinicopathologic features and the possible histogenesis of this tumor and suggests a role for stilbestrol in its development.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / drug therapy
  • Adenocarcinoma / genetics
  • Adenocarcinoma / pathology*
  • Aged
  • Carcinoma, Squamous Cell / drug therapy
  • Carcinoma, Squamous Cell / genetics
  • Carcinoma, Squamous Cell / pathology*
  • DNA, Neoplasm / analysis
  • Diethylstilbestrol / adverse effects
  • Diethylstilbestrol / therapeutic use*
  • Humans
  • Immunohistochemistry
  • Male
  • Neoplasms, Hormone-Dependent / pathology*
  • Prostatic Neoplasms / drug therapy
  • Prostatic Neoplasms / genetics
  • Prostatic Neoplasms / pathology*


  • DNA, Neoplasm
  • Diethylstilbestrol